Dr Abdelmoneim was born and raised in the UK to Sudanese Iranian parents. He graduated in medicine from University College London in 2003 and undertook postgraduate training in emergency medicine. After gaining MRCP (Membership of the Royal College of Physicians, London) and obtaining a diploma in tropical medicine, he joined Médecins Sans Frontières (MSF) in 2009 as a field volunteer and spent six months in Iraq then another six in Haiti.

Since then, he has worked on MSF projects in Lebanon for Syria, South Sudan and Sierra Leone during the Ebola crisis, where he wore a miniature camera attached to his goggles, to provide a unique ‘Dr’s eye view’ inside the high risk zone for the BBC programme Panorama.  In the summer of 2015 he joined the MSF UK board as a trustee of the organization.

Dr Abdelmoneim has presented BBC series No More Boys and Girls, How to Lose Weight Well and documentary The Truth About Alcohol.

Dr Abdelmoneim works as an emergency medicine registrar in Chelsea & Westminster hospital in London and is a presenter on Al Jazeera’s The Cure, a series looking at some of the world’s most intractable health problems and the inspirational people working to find a cure.

In 2022, Dr Abdelmoneim returned to MSF full-time.